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PPARA Antibody#37219

PPARA Antibody
PPARA Antibody
是否有货: 有货
产品总价:
产品详情

产品名称PPARA Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antigen affinity purification.

应用WB IHC

种属反应性Hu Ms Rt

特异性The antibody detects endogenous levels of total PPARA protein.

免疫原类型Peptide

免疫原描述Synthetic peptide corresponding to residues near the N terminal of human Peroxisome proliferator-activated receptor alpha

基因/蛋白名称PPARA

别名PPAR; NR1C1; hPPAR; PPARalpha

数据库入口号Swiss-Prot#: Q07869
NCBI Gene ID: 5465
Gene Accssion: NP_005027

UniprotQ07869

实际分子量52kd

浓度1mg/ml

配方Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.

保存Store at -20˚C

应用详情
Western blotting: 1:200-1:1000
Immunohistochemistry: 1:25-1:100
Gel: 10%SDS-PAGE
Lysates (from left to right): 231 and Jurkat cell
Amount of lysate: 40ug per lane
Primary antibody: 1/500 dilution
Secondary antibody dilution: 1/8000
Exposure time: 2 minutes
Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue using #37219 at dilution 1/30.
背景
Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined.

如果您使用该产品37219发表了文章,请通知我们,让我们可以引用您的文献。

et al,Fenofibrate suppressed proliferation and migration of human neuroblastoma cells via oxidative stress dependent of TXNIP upregulation.In Biochem Biophys Res Commun on 2015 May 15 by Cunjin Su, Aiming Shi et al..PMID:25839662, , (2015),
PMID: 25839662
5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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