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Smad1/Smad5/Smad8 Antibody#21684

Smad1/Smad5/Smad8 Antibody
是否有货: 有货
产品总价:
产品详情

产品名称Smad1/Smad5/Smad8 Antibody

来源种属Rabbit

克隆性Polyclonal

应用WB

种属反应性Hu Ms Rt

特异性The antibody detects endogenous level of total Smad1, Smad5, Smad8 protein.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around aa.461-465(I-S-S-V-S) derived from Human Smad1. This sequence has the same homology in Smad5 and Smad8.

基因/蛋白名称Smad1/Smad5/Smad8

别名 Mad-related protein 1, SMAD 1, hSMAD1, Transforming growth factor-beta-signaling protein 1,

浓度1.0mg/ml

应用详情
Predicted MW: 60kd
Western blotting: 1: 500~1: 1000
Western blot analysis of extracts from 3T3 cells using Smad1/Smad5/Smad8 Antibody #21684.
背景
Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD).SMAD5 is a receptor-regulated SMAD (R-SMAD). SMAD9 is a receptor-regulated SMAD (R-SMAD). Has been shown to be activated by activin type I receptor-like kinases (ALK-2, ALK-3, ALK-6) which stimulate heteromerization between SMAD9 and SMAD4. May play a role in osteoblast differentiation and maturation.

如果您使用该产品21684发表了文章,请通知我们,让我们可以引用您的文献。

et al,Vital Roles of Gremlin-1 in Pulmonary Arterial Hypertension Induced by Systemic-to-Pulmonary Shunts. In J Am Heart Assoc on 2020 Aug 4 by Liukun Meng, Xiao Teng, et al..PMID: 32750294, , (2020),
PMID: 32750294
et al,Inhibition of TGF尾 signaling decreases osteogenic differentiation of fibrodysplasia ossificans progressiva fibroblasts in a novel in vitro model of the disease.In Bone.On 2016 Mar by Micha D, Voermans E et al..PMID:26769004, , (2016),
PMID: 26769004
5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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