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CD8 Antibody#47992

CD8 Antibody
是否有货: Yes
产品总价:
产品详情

产品名称CD8 Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Immunogen affinity purified

应用WB, ICC, IHC, FC

种属反应性Ms

免疫原描述peptide

别名CD8 antibody
CD8 antigen, alpha polypeptide (p32) antibody
CD8a antibody
CD8a antigen antibody
CD8a molecule antibody
CD8A_HUMAN antibody
Leu2 antibody
Leu2 T lymphocyte antigen antibody
MAL antibody
OKT8 T cell antigen antibody
p32 antibody
T cell antigen Leu2 antibody
T cell co receptor antibody
T-cell surface glycoprotein CD8 alpha chain antibody
T-lymphocyte differentiation antigen T8/Leu-2 antibody
T8 T cell antigen antibody

数据库入口号Swiss-Prot#:P01731

计算分子量32-36kDa

配方1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

保存Store at -20˚C

应用详情
WB: 1:500



Western blot analysis on mouse Thymus using anti-CD8 polyclonal antibody
背景
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. Cluster of Differentiation 8 (CD8) is a disulphide-linked heterodimer consisting of the unrelated α and β subunits. Each subunit is a glycoprotein composed of a single extracellular Ig-like domain, a polypeptide linker, a transmembrane part and a short cytoplasmic tail. CD8 alpha chains binds to class I MHC molecules alpha-3 domains. CD8 is thought to play a role in the process of T-cell mediated killing.
背景文献
1.Liaw C.W., Zamoyska R., Parnes J.R.; "Structure, sequence, and polymorphism of the Lyt-2 T cell differentiation antigen gene."; J. Immunol. 137:1037-1043(1986).
2.Youn H.J., Harriss J.V., Gottlieb P.D.; "Nucleotide sequence analysis of the C.AKR Lyt-2a gene: structural polymorphism in alleles encoding the Lyt-2.1 T-cell surface alloantigen."; Immunogenetics 28:345-352(1988).
3.Zamoyska R., Vollmer A.C., Sizer K.C., Liaw C.W., Parnes J.R.; "Two Lyt-2 polypeptides arise from a single gene by alternative splicing patterns of mRNA."; Cell 43:153-163(1985).

如果您使用该产品47992发表了文章,请通知我们,让我们可以引用您的文献。

et al,Salinomycin promotes T-cell proliferation by inhibiting the expression and enzymatic activity of immunosuppressive indoleamine-2,3-dioxygenase in human breast cancer cells. In Toxicol Appl Pharmacol on 2020 Oct 1 by Yuwen Sheng, Zhonghui Zhang, et al..PMID:32822738, , (2020),
PMID: 32822738
5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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