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c-Fos Antibody#48283

c-Fos Antibody
c-Fos Antibody
是否有货: Yes
产品总价:
产品详情

产品名称c-Fos Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Immunogen affinity purified

应用WB, IP, IF, IHC(P)

种属反应性Hu, Ms, Rt, Fish

免疫原描述peptide

别名Activator protein 1 antibody
AP 1 antibody
C FOS antibody
Cellular oncogene c fos antibody
Cellular oncogene fos antibody
FBJ murine osteosarcoma viral (v fos) oncogene homolog (oncogene FOS) antibody
FBJ murine osteosarcoma viral oncogene homolog antibody
FBJ murine osteosarcoma viral v fos oncogene homolog antibody
FBJ Osteosarcoma Virus antibody
FOS antibody
FOS protein antibody
FOS_HUMAN antibody
G0 G1 switch regulatory protein 7 antibody
G0/G1 switch regulatory protein 7 antibody
G0S7 antibody
Oncogene FOS antibody
p55 antibody
proto oncogene c Fos antibody
Proto oncogene protein c fos antibody
Proto-oncogene c-Fos antibody
v fos FBJ murine osteosarcoma viral oncogene homolog antibody

数据库入口号Swiss-Prot#:P01100

计算分子量62kDa

配方1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

保存Store at -20˚C

应用详情

WB: 1:100-1:1,000
IHC: 1:50-1:500

IP: 1-2 μg per 100-500 μg of total protein (1 ml of cell lysate)

Western blot analysis of c-Fos expression in non-transfected(A) and mouse c-Fos transfected(B) 293T whole cell lysates.
Nuclear immunofluorescence staining of methanol-fixed, phorbol ester-induced HeLa cells (A) and formalin-fixed HepG2 cells showing nuclear localization (B).
背景

The c-Fos oncogene was initially detected in two independent murine osteosarcoma virus isolates and an avian nephroblastoma virus. The cellular homolog, c-Fos, encodes a nuclear phospho-protein that is rapidly and transiently induced by a variety of agents and functions as a transcriptional regulator for several genes. In contrast to c-Jun proteins, which form homo- and heterodimers which bind to specific DNA response elements, c-Fos proteins are only active as heterodimers with members of the Jun gene family. Functional homologs of c-Fos include the Fra-1, Fra-2 and Fos B genes. In addition, selected ATF/CREB family members can form leucine zipper dimers with Fos and Jun. Different dimers exhibit differential specificity and affinity for AP-1 and CRE sites.

背景文献

1. Tsuneoka, Y., et al. 2013. Functional, anatomical, and neurochemical differentiation of medial preoptic area subregions in relation to maternal behavior in the mouse. J. Comp. Neurol. 521: 1633-1663.
2. Shimizu, T., et al. 2013. Stimulatory and inhibitory roles of brain 2-arachidonoylglycerol in bombesin-induced central activation of adrenomedullary outflow in rats. J. Pharmacol. Sci. 121: 157-171.

如果您使用该产品48283发表了文章,请通知我们,让我们可以引用您的文献。

et al,Inhibitory Effects of Combined Bone Morphogenetic Protein 2, Vascular Endothelial Growth Factor, and Basic Fibroblast Growth Factor on Osteoclast Differentiation and Activity. In Tissue Eng Part A on 2021 Nov by Huan Wu, Guangfu Yin,et al..PMID:33632010, , (2021),
PMID: 33632010
5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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025-58868422

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