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位置: 首页 > 重组兔单抗 > NLRP3 Rabbit mAb

NLRP3 Rabbit mAb#49012

评价
Recombinant
NLRP3 Rabbit mAb
NLRP3 Rabbit mAb
NLRP3 Rabbit mAb
NLRP3 Rabbit mAb
NLRP3 Rabbit mAb
NLRP3 Rabbit mAb
是否有货: Yes
产品总价:
产品详情

产品名称NLRP3 Rabbit mAb

来源种属Recombinant Rabbit

克隆性 Monoclonal antibody

克隆性SC06-23

纯化ProA affinity purified

应用WB, ICC/IF, IHC, IP, FC

种属反应性Hu, Ms, Rt

免疫原描述recombinant protein

别名AGTAVPRL antibody
AII/AVP antibody
Angiotensin/vasopressin receptor AII/AVP like antibody
Angiotensin/vasopressin receptor AII/AVP-like antibody
C1orf7 antibody
Caterpiller protein 1.1 antibody
CIAS 1 antibody
CIAS1 antibody
CLR1.1 antibody
Cold autoinflammatory syndrome 1 antibody
Cold autoinflammatory syndrome 1 protein antibody
Cryopyrin antibody
Familial cold autoinflammatory syndrome antibody
FCAS antibody
FCU antibody
LRR and PYD domains-containing protein 3 antibody
Muckle-Wells syndrome antibody
MWS antibody
NACHT antibody
NACHT LRR and PYD containing protein 3 antibody
NALP 3 antibody
NALP3 antibody
NALP3_HUMAN antibody
NLRP3 antibody
PYPAF 1 antibody
PYPAF1 antibody
PYRIN containing APAF1 like protein 1 antibody
PYRIN-containing APAF1-like protein 1 antibody

数据库入口号Swiss-Prot#:Q96P20

计算分子量118/85 kDa

配方1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

保存Store at -20˚C

应用详情
WB: 1:1,000
IHC: 1:50-1:200
ICC: 1:100-1:500

FC: 1:50-1:100
背景
Cryopyrin interacts selectively with apoptosis-associated specklike protein containing a CARD domain (ASC). This complex may function as an upstream activator of NFkB signaling and caspase-1 activation. The complex also inhibits TNFa induced activation and nuclear translocation of RelA/NFkB p65. Mutations in Cryopyrin and Pyrin proteins are responsible for several autoinflammatory disorders in humans, including familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS) and chronic infantile neurologic cutaneous and articular syndrome (CINCA).
背景文献
1. Qiao J et al. Busulfan and cyclosphamide induce liver inflammation through NLRP3 activation in mice after hematopoietic stem cell transplantation. Sci Rep 5:17828 (2015).
2. Ataide MA et al. Malaria-induced NLRP12/NLRP3-dependent caspase-1 activation mediates inflammation and hypersensitivity to bacterial superinfection. PLoS Pathog 10:e1003885 (2014).

如果您使用该产品49012发表了文章,请通知我们,让我们可以引用您的文献。

et al,Neuro-immune interaction in CNS injury and diseaseInImmunol RevOn2023 Mar 1byB Li, G Ning et al..PMID:35067941, , (2023),
PMID: 35067941
et al,Interventional Efects of the Topical of "Sanse Powder" Essential Oils Nanoemulsion on Knee Osteoarthritis in Rats by Targeting the ERS/TXNIP/NLRP3 Signaling Axis.In Front Pharmacol on 2021 Sep 2 by Zixiu Liu, Taiyang Liao, et al.., , (2021),
PMID: 34539417
et al,Interventional Efects of the Topical of "Sanse Powder" Essential Oils Nanoemulsion on Knee Osteoarthritis in Rats by Targeting the ERS/TXNIP/NLRP3 Signaling Axis.In Front Pharmacol on 2021 Sep 2 by Zixiu Liu, Taiyang Liao, et al..PMID: 34539417, , (2021),
PMID: 34539417
et al,Monotropein alleviates secondary liver injury in chronic colitis by regulating TLR4/NF-kB signaling and NLRP3 inflammasome . In Eur J Pharmacol on 2020 Sep 15 by Yonger Chen , Yingyu Lu, et al..PMID:32710952, , (2020), , (2020),
PMID: 32710952
et al,Ginsenoside Rk3 alleviated DSS-induced ulcerative colitis by protecting colon barrier and inhibiting NLRP3 inflammasome pathway. In Int Immunopharmacol on 2020 Aug by Mi Tian, Pei Ma, et al..PMID: 32521491, , (2020),
PMID: 32521491
5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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