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c-Fos Rabbit mAb

49310
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  货号 规格 价格
49310-1 50ul ¥2000.00元
49310-2 100ul ¥3000.00元

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产品详情
  • 产品名称 c-Fos Rabbit mAb
  • 来源种属 Recombinant Rabbit
  • 克隆性 Monoclonal antibody
  • 克隆号 JJ0938
  • 纯化 ProA affinity purified
  • 应用 WB, FC
  • 种属反应性 Hu, Ms, Rt
  • 免疫原描述 recombinant protein
  • 别名 Activator protein 1 antibody
    AP 1 antibody
    C FOS antibody
    Cellular oncogene c fos antibody
    Cellular oncogene fos antibody
    FBJ murine osteosarcoma viral (v fos) oncogene homolog (oncogene FOS) antibody
    FBJ murine osteosarcoma viral oncogene homolog antibody
    FBJ murine osteosarcoma viral v fos oncogene homolog antibody
    FBJ Osteosarcoma Virus antibody
    FOS antibody
    FOS protein antibody
    FOS_HUMAN antibody
    G0 G1 switch regulatory protein 7 antibody
    G0/G1 switch regulatory protein 7 antibody
    G0S7 antibody
    Oncogene FOS antibody
    p55 antibody
    proto oncogene c Fos antibody
    Proto oncogene protein c fos antibody
    Proto-oncogene c-Fos antibody
    v fos FBJ murine osteosarcoma viral oncogene homolog antibody
  • 数据库入口号 Swiss-Prot#:P01100
  • 计算分子量 62 kDa
  • 配方1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • 保存 Store at -20˚C
应用详情

WB: 1:1,000



FC: 1:50-1:100

图片
  • c-Fos Rabbit mAb - SAB | Signalway Antibody

    Flow cytometric analysis of NIH/3T3 cells with c-Fos antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.

背景
The c-Fos oncogene was initially detected in two independent murine osteosarcoma virus isolates and an avian nephroblastoma virus. The cellular homolog, c-Fos, encodes a nuclear phospho-protein that is rapidly and transiently induced by a variety of agents and functions as a transcriptional regulator for several genes. In contrast to c-Jun proteins, which form homo- and heterodimers which bind to specific DNA response elements, c-Fos proteins are only active as heterodimers with members of the Jun gene family. Functional homologs of c-Fos include the Fra-1, Fra-2 and Fos B genes. In addition, selected ATF/CREB family members can form leucine zipper dimers with Fos and Jun. Different dimers exhibit differential specificity and affinity for AP-1 and CRE sites.
背景文献
1. Dantas-Ferreira, R.F. et al. 2015. Food-anticipatory activity in Syrian hamsters: behavioral and molecular responses in the hypothalamus according to photoperiodic conditions. PloS one. 10: e0126519.
2. Zhang, J. et al. 2015. Effect of BioAggregate on Receptor Activator of Nuclear Factor-Kappa B Ligand-induced Osteoclastogenesis from Murine Macrophage Cell Line In Vitro. Journal of endodontics. 41: 1265-71.
  • et al,Curcumin induces apoptosis and inhibits the growth of adrenocortical carcinoma: Identification of potential candidate genes and pathways by transcriptome analysis. In Oncol Lett on 2021 Jun by Xuemei Huang, Chunfeng Liang,et al..PMID:33907586, , (2021),
    PMID: 33907586
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    注释
      应用:
    • WB免疫印迹
    • IHC免疫组化
    • IF免疫荧光
    • ICC免疫细胞化学
    • FC流式细胞
    • IP免疫沉淀
    • E酶联免疫吸附法
    • DB免疫斑点法
    • ChIP染色质免疫沉淀
    • GICA胶体金免疫层析法
    • NC阴性对照
      种属反应性:
    • Hu
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    • Dm果蝇
    • C线虫
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