产品详情
产品名称c-Fos Rabbit mAb
来源种属Recombinant Rabbit
克隆性 Monoclonal antibody
克隆性JJ0938
纯化ProA affinity purified
应用WB, FC
种属反应性Hu, Ms, Rt
免疫原描述recombinant protein
别名Activator protein 1 antibody AP 1 antibody C FOS antibody Cellular oncogene c fos antibody Cellular oncogene fos antibody FBJ murine osteosarcoma viral (v fos) oncogene homolog (oncogene FOS) antibody FBJ murine osteosarcoma viral oncogene homolog antibody FBJ murine osteosarcoma viral v fos oncogene homolog antibody FBJ Osteosarcoma Virus antibody FOS antibody FOS protein antibody FOS_HUMAN antibody G0 G1 switch regulatory protein 7 antibody G0/G1 switch regulatory protein 7 antibody G0S7 antibody Oncogene FOS antibody p55 antibody proto oncogene c Fos antibody Proto oncogene protein c fos antibody Proto-oncogene c-Fos antibody v fos FBJ murine osteosarcoma viral oncogene homolog antibody
数据库入口号Swiss-Prot#:P01100
计算分子量62 kDa
配方1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
保存Store at -20˚C
应用详情
WB: 1:1,000
FC: 1:50-1:100
背景
The c-Fos oncogene was initially detected in two independent murine osteosarcoma virus isolates and an avian nephroblastoma virus. The cellular homolog, c-Fos, encodes a nuclear phospho-protein that is rapidly and transiently induced by a variety of agents and functions as a transcriptional regulator for several genes. In contrast to c-Jun proteins, which form homo- and heterodimers which bind to specific DNA response elements, c-Fos proteins are only active as heterodimers with members of the Jun gene family. Functional homologs of c-Fos include the Fra-1, Fra-2 and Fos B genes. In addition, selected ATF/CREB family members can form leucine zipper dimers with Fos and Jun. Different dimers exhibit differential specificity and affinity for AP-1 and CRE sites.
背景文献
1. Dantas-Ferreira, R.F. et al. 2015. Food-anticipatory activity in Syrian hamsters: behavioral and molecular responses in the hypothalamus according to photoperiodic conditions. PloS one. 10: e0126519. 2. Zhang, J. et al. 2015. Effect of BioAggregate on Receptor Activator of Nuclear Factor-Kappa B Ligand-induced Osteoclastogenesis from Murine Macrophage Cell Line In Vitro. Journal of endodontics. 41: 1265-71.
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et al,Curcumin induces apoptosis and inhibits the growth of adrenocortical carcinoma: Identification of potential candidate genes and pathways by transcriptome analysis. In Oncol Lett on 2021 Jun by Xuemei Huang, Chunfeng Liang,et al..PMID:33907586,
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PMID: 33907586
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