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DDC Antibody#43658

DDC Antibody
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产品总价:
产品详情

产品名称DDC Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antigen affinity purification

应用WB

种属反应性Hu

特异性The antibody detects endogenous levels of total DDC protein.

免疫原类型peptide

免疫原描述Synthetic peptide of human DDC

基因/蛋白名称DDC

别名AADC

数据库入口号Swiss-Prot#: P20711
NCBI Gene ID: 1644

UniprotP20711

计算分子量54kd

浓度0.7mg/ml

配方Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

保存Store at -20˚C

应用详情
Western blotting: 1:500-2000
Gel: 8%SDS-PAGE
Lysate: 40 μg, Lane 1-2: Human left kidney tissue and Human fetal liver tissue lysates,
Primary antibody:DDC antibody at dilution 1/800,
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,
Exposure time: 10 seconds
背景
The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

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et al,5-HT2A Receptor and 5-HT Degradation Play a Crucial Role in Atherosclerosis by Modulating Macrophage Foam Cell Formation, Vascular Endothelial Cell Inflammation, and Hepatic Steatosis. In J Atheroscler Thromb on 2021 Feb 2 by Yingying Ma, Xiurui Liang,et al..PMID: 33536397, , (2021),
PMID: 33536397
5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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