产品详情
产品名称KCNA10 antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification
应用IHC
种属反应性Hu, Ms
免疫原描述Synthetic peptide of human KCNA10
基因/蛋白名称KCNA10
别名Kcn1; Kv1.8
数据库入口号Swiss-Prot#: Q07627
NCBI Gene ID: NP_005540
浓度0.7mg/ml
配方pH7.4 PBS, 0.05% NaN3, 40% Glycerol
保存Store at -20˚C/1 year
应用详情
IHC dilution:1:30-1:150
背景
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It is specifically regulated by cGMP and postulated to mediate the effects of substances that increase intracellular cGMP. This gene is intronless, and the gene is clustered with genes KCNA2 and KCNA3 on chromosome 1.?