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Occludin Rabbit Polyclonal Antibodies

29275
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29275-1 50ul ¥1200.00元
29275-2 100ul ¥2000.00元

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产品详情
  • 产品名称 Occludin Rabbit Polyclonal Antibodies
  • 来源种属 Rabbit
  • 克隆性 Polyclonal
  • 亚型 IgG
  • 纯化 Affinity purification
  • 应用 WB IHC IF
  • 种属反应性 Human,Mouse,Rat
  • 免疫原描述 Recombinant fusion protein of human Occludin (NP_002529.1).
  • 别名 OCLN;BLCPMG;PPP1R115;PTORCH1;occludin;Occludin
  • 数据库入口号 Swiss-Prot#:Q16625
    NCBI Gene ID:100506658
  • 计算分子量 8kDa/23kDa/31kDa/52kDa/54kDa/59kDa
  • 配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.
  • 保存 Store at -20˚C. Avoid freeze / thaw cycles.
应用详情

WB 1:1000 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200

图片
  • Occludin Rabbit Polyclonal Antibodies - SAB | Signalway Antibody

    Western blot analysis of extracts of various cell lines, using Occludin at 1:1000 dilution.

  • Occludin Rabbit Polyclonal Antibodies - SAB | Signalway Antibody

    Immunohistochemistry of paraffin-embedded rat ovary using Occludin Rabbit pAb at dilution of 1:100 (40x lens).

  • Occludin Rabbit Polyclonal Antibodies - SAB | Signalway Antibody

    Immunohistochemistry of paraffin-embedded human colon using Occludin Rabbit pAb at dilution of 1:100 (40x lens).

  • Occludin Rabbit Polyclonal Antibodies - SAB | Signalway Antibody

    Immunofluorescence analysis of HeLa cells using Occludin at dilution of 1:100. Blue: DAPI for nuclear staining.

  • Occludin Rabbit Polyclonal Antibodies - SAB | Signalway Antibody

    Immunofluorescence analysis of NIH/3T3 cells using Occludin at dilution of 1:100. Blue: DAPI for nuclear staining.

  • Occludin Rabbit Polyclonal Antibodies - SAB | Signalway Antibody

    Immunofluorescence analysis of PC12 cells using Occludin at dilution of 1:100. Blue: DAPI for nuclear staining.

背景

This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5.

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