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位置: 首页 > 抗体 > LOXL1 Rabbit Polyclonal Antibody

LOXL1 Rabbit Polyclonal Antibody#29553

LOXL1 Rabbit Polyclonal Antibody
LOXL1 Rabbit Polyclonal Antibody
是否有货: Yes
产品总价:
产品详情

产品名称LOXL1 Rabbit Polyclonal Antibody

来源种属Rabbit

克隆性Polyclonal

亚型IgG

纯化Affinity purification

应用WB,IF

种属反应性Human,Mouse,Rat

免疫原描述Recombinant fusion protein of human LOXL1 (NP_005567.2).

别名LOXL1;LOL;LOXL

数据库入口号Swiss Prot:Q08397
GeneID:4016

计算分子量63kDa

实际分子量80kDa

配方Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

保存Store at -20˚C. Avoid freeze / thaw cycles.

应用详情

WB 1:1000 - 1:3000
IF 1:50 - 1:200

Western blot analysis of extracts of various cell lines, using LOXL1 at 1:1000 dilution.
Immunofluorescence analysis of mouse eye using LOXL1 Polyclonal at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
背景

This gene encodes a member of the lysyl oxidase family of proteins. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyzes the first step in the formation of crosslinks in collagen and elastin. The encoded preproprotein is proteolytically processed to generate the mature enzyme. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. Mutations in this gene are associated with exfoliation syndrome.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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