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位置: 首页 > 重组蛋白 > Recombinant human Probable G-protein coupled receptor 75

Recombinant human Probable G-protein coupled receptor 75#AP70357

是否有货: 15-30工作日
产品总价:
产品详情

产品名称Recombinant human Probable G-protein coupled receptor 75

来源种属E.coli

基因/蛋白名称GPR75

数据库入口号Uniprot ID: O95800

目标蛋白种属HUMAN

计算分子量34.9kD

蛋白长度Full length of Cytoplasmic, 372-540aa

标签信息N-terminal 10*His-SUMO-tagged

序列NPFIYSRNSAGLRRKVLWCLQYIGLGFFCCKQKTRLRAMGKGNLEVNRNKSSHHETNSAYMLSPKPQKKFVDQACGPSHSKESMVSPKISAGHQHCGQSSSTPINTRIEPYYSIYNSSPSQEESSPCNLQPVNSFGFANSYIAMHYHTTNDLVQEYDSTSAKQIPVPSV

配方20mM Tris-HCl based buffer,pH8.0

保存Store at -20˚C, for extended storage, conserve at -20˚C or -80˚C. Repeated freezing and thawing is not recommended. Store working aliquots at 4˚C for up to one week.

应用详情

Purity: Greater than 90% as determined by SDS-PAGE.

背景

G protein-coupled receptor that is activated by the chokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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