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位置: 首页 > 磷酸化抗体 > YY1 (Phospho-Ser187) Antibody

YY1 (Phospho-Ser187) Antibody #SAB654

是否有货: Yes
产品总价:
产品详情

产品名称YY1 (Phospho-Ser187) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化The antibody was purified from rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.

应用WB

种属反应性Human

特异性YY1(Phospho-Ser187) Antibody detects endogenous levels of YY1( only when phosphorylated at Ser187.

免疫原描述A synthesized peptide derived from human YY1 around the phosphorylation site of Ser187.

别名YY1,INO80S,NF-E1,YY-1,Delta transcription factor

UniprotP25490

Gene ID7528

实际分子量44kDa

浓度1 mg/ml

配方Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl,0.02% sodium azide.

保存Store at --20˚C/1 year

应用详情
Western Blot: 1/500 - 1/2000
背景
Multifunctional transcription factor that exhibits positive and negative control on a large number of cellular and viral genes by binding to sites overlapping the transcription start site. Binds to the consensus sequence 5'-CCGCCATNTT-3'; some genes have been shown to contain a longer binding motif allowing enhanced binding; the initial CG dinucleotide can be methylated greatly reducing the binding affinity. The effect on transcription regulation is depending upon the context in which it binds and diverse mechanisms of action include direct activation or repression, indirect activation or repression via cofactor recruitment, or activation or repression by disruption of binding sites or conformational DNA changes. Its activity is regulated by transcription factors and cytoplasmic proteins that have been shown to abrogate or completely inhibit YY1-mediated activation or repression.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

联系我们

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400-9961-933
025-58868422

Email Address

techcn@signalwayantibody.com