产品名称Dacogen

简述Inhibitors

纯化99.00%

生物活性Decitabine is indicated for treatment of patients with myelodysplastic syndrome (MDS). It is a chemical analogue of cytidine, a nucleoside present in DNA and RNA. Cells in the presence of Decitabine incorporate it into DNA during replication and RNA during transcription. The incorporation of Decitabine into DNA or RNA inhibits methyltransferase thereby causing demethylation in that sequence. This adversely affects the way that cell regulatory proteins are able to bind to the DNA/RNA substrate.

基因/蛋白名称DNA Methyltransferase inhibitor

CAS号2353-33-5

计算分子量228.21

配方C8H12N4O4

保存3 years -20˚C powder;2 years -80˚C in solvent;