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位置: 首页 > 抗体 > EGFR(Ab-1172) Antibody

EGFR(Ab-1172) Antibody#21213

EGFR(Ab-1172) Antibody
是否有货: 有货
产品总价:
产品详情

产品名称EGFR(Ab-1172) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

应用WB

种属反应性Hu Ms Rt

特异性The antibody detects endogenous level of total EGFR protein.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around aa. 1170~1174 (P-D-Y-Q-Q) derived from Human EGFR.

基因/蛋白名称EGFR

别名Receptor tyrosine-protein kinase ErbB-1

数据库入口号Swiss-Prot: P00533
NCBI Protein: NP_005219.2

浓度1.0mg/ml

配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

应用详情
Predicted MW: 175kd
Western blotting: 1:500~1:1000
Western blot analysis of extracts from HUVEC cells using EGFR(Ab-1172) Antibody #21213.
背景
Receptor for EGF, but also for other members of the EGF family, as TGF-a, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. Phosphorylates MUC1 in breast cancer cells and increases the interaction of MUC1 with SRC and CTNNB1/beta-catenin.

Noguchi T, et al. (1994) Mol Cell Biol; 14(10): 6674-6682
Doherty JK, et al. (1999) Proc Natl Acad Sci U S A; 96(19): 10869-10874
Kanner SB, et al. (1991) Mol Cell Biol; 11(2): 713-720
Wu TT, et al. (1998) Mol Biol Cell; 9(7): 1661-1674
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如果您使用该产品21213发表了文章,请通知我们,让我们可以引用您的文献。

et al,ZD6474, a new treatment strategy for human osteosarcoma, and its potential synergistic effect with celecoxib銆侷n Oncotarget on 2015 Aug 28 by Jiani Liu, Jiangxue Wu et al..PMID: 26050198, , (2015),
PMID: 26050198
et al,ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect.In Nat Cell Biol on 2012 Dec by Weiwei Yang, Yanhua Zheng,et al..PMID:23178880, , (2012),
PMID: 23178880
5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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