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ANP32A Antibody

33030
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  货号 规格 价格
33030-1 50ul ¥1200.00元
33030-2 100ul ¥2000.00元

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产品详情
  • 产品名称 ANP32A Antibody
  • 来源种属 Rabbit
  • 克隆性 Polyclonal
  • 亚型 IgG
  • 纯化 Affinity purification
  • 应用 WB,IHC
  • 种属反应性 Human,Mouse,Rat
  • 特异性The antibody detects endogenous level of total ANP32A protein.
  • 免疫原类型Recombinant Protein
  • 免疫原描述 Recombinant fusion protein of human ANP32A (NP_006296.1).
  • 基因/蛋白名称 ANP32A
  • 别名 ANP32A;C15orf1;HPPCn;I1PP2A;LANP;MAPM;PHAP1;PHAPI;PP32
  • Uniprot号 P39687
  • Gene ID号 8125
  • 数据库入口号 Uniprot:P39687
    GeneID:8125
  • 实际分子量 28kDa
  • 浓度 1.0mg/ml
  • 配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.
  • 保存 Store at -20˚C. Avoid freeze / thaw cycles.
应用详情

WB 1:500 - 1:2000
IHC 1:50 - 1:200

图片
  • ANP32A Antibody - SAB | Signalway Antibody

    Western blot analysis of extracts of various cell lines, using ANP32A antibody.

  • ANP32A Antibody - SAB | Signalway Antibody

    Immunohistochemistry of paraffin-embedded rat kidney using ANP32A Antibody.

  • ANP32A Antibody - SAB | Signalway Antibody

    Immunohistochemistry of paraffin-embedded human breast cancer using ANP32A Antibody.

  • ANP32A Antibody - SAB | Signalway Antibody

    Immunohistochemistry of paraffin-embedded mouse brain using ANP32A Antibody.

背景
Multifunctional protein that is involved in the regulation of many processes including tumor suppression, apoptosis, cell cycle progression or transcription. Promotes apoptosis by favouring the activation of caspase-9/CASP9 and allowing apoptosome formation. In addition, plays a role in the modulation of histone acetylation and transcription as part of the INHAT (inhibitor of histone acetyltransferases complex. Inhibits the histone-acetyltranferase activity of EP300/CREBBP (CREB-binding protein and EP300/CREBBP-associated factor by histone masking. Preferentially binds to unmodified histone H3 and sterically inhibiting its acetylation and phosphorylation leading to cell growth inhibition. Participates in other biochemical processes such as regulation of mRNA nuclear-to-cytoplasmic translocation and stability by its association with ELAVL1 (Hu-antigen R. Plays a role in E4F1-mediated transcriptional repression as well as inhibition of protein phosphatase 2A.
  • et al,Paroxetine Attenuates Cardiac Hypertrophy Via Blocking GRK2 and ADRB1 Interaction in Hypertension. In J Am Heart Assoc on 2021 Jan 5 by Xuejing Sun, Mengli Zhou, et al..PMID:33372534, , (2021),
    PMID: 33372534
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      应用:
    • WB免疫印迹
    • IHC免疫组化
    • IF免疫荧光
    • ICC免疫细胞化学
    • FC流式细胞
    • IP免疫沉淀
    • E酶联免疫吸附法
    • DB免疫斑点法
    • ChIP染色质免疫沉淀
    • GICA胶体金免疫层析法
    • NC阴性对照
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