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Bak Antibody#33326

Bak Antibody
Bak Antibody
是否有货: 有货
产品总价:
产品详情

产品名称Bak Antibody

来源种属Rabbit

克隆性Polyclonal

纯化The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

应用WB IHC IF

种属反应性Hu

特异性The antibody detects endogenous levels of total Bak protein.

免疫原类型Peptide

免疫原描述Synthesized peptide derived from human Bak.

基因/蛋白名称Bak

别名Bcl-2 homologous antagonist/killer; Apoptosis regulator BAK; Bcl-2-like 7 protein; BAK1; BAK

数据库入口号Swiss-Prot: Q16611
NCBI Gene ID: 578

UniprotQ16611

实际分子量25kd

浓度1.0mg/ml

配方Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20˚C

应用详情
Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
Western blot analysis of extracts from 293 cells, using Bak antibody #33326.
Immunohistochemical analysis of paraffin-embedded human skeletal muscle tissue using Bak antibody #33326.
背景
In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the anti-apoptotic action of BCL2 or its adenovirus homolog E1B 19k protein. Low micromolar levels of zinc ions inhibit the promotion of apoptosis.

Takuma Uo, J. Biol. Chem., Mar 2005; 280: 9065 - 9073.
Pierre-Fran?ois Cartron, Mol. Cell. Biol., Jul 2003; 23: 4701 - 4712.
Joslyn K. Brunelle, J. Biol. Chem., Feb 2004; 279: 4305 - 4312.
Neil A. Jones, Mol. Pharmacol., May 1998; 53: 819.

如果您使用该产品33326发表了文章,请通知我们,让我们可以引用您的文献。

et al,IFN-γ restores the impaired function of RNase L and induces mitochondria-mediated apoptosis in lung cancer. In Cell Death Dis on 2019 Sep 9 by Huijing Yin, Zhengyu Jiang, et al..PMID: 31501431, , (2019),
PMID: 31501431
5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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025-58868422

Email Address

techcn@signalwayantibody.com