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HBP1 Antibody#33596

HBP1 Antibody
是否有货: 有货
产品总价:
产品详情

产品名称HBP1 Antibody

来源种属Rabbit

克隆性Polyclonal

纯化The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

应用WB

种属反应性Hu Ms Rt

特异性The antibody detects endogenous levels of total HBP1 protein.

免疫原类型Peptide

免疫原描述Synthesized peptide derived from Internal of human HBP1.

基因/蛋白名称HBP1

别名HMG box-containing protein 1; HMG box-containing protein 1; High mobility group box transcription factor 1; HBP1;

数据库入口号Swiss-Prot: O60381
NCBI Gene ID: 26959

UniprotO60381

实际分子量57kd

浓度1.0mg/ml

配方Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20˚C

应用详情
Western blotting: 1:500~1:3000

Western blot analysis of extracts from COS-7 cells, using HBP1 antibody #33596.
背景
Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.

Lemercier C., Mol. Cell. Biol. 20:6627-6637(2000).
Hillier L.W., Nature 424:157-164(2003).
Ota T., Nat. Genet. 36:40-45(2004).

如果您使用该产品33596发表了文章,请通知我们,让我们可以引用您的文献。

et al,Focused screening of mitochondrial metabolism reveals a crucial role for a tumor suppressor Hbp1 in ovarian reserve.In Cell Death Differ on 2016 Oct by Z Dong , M Huang et al..PMID:27206316 , , (2016),
PMID: 27206316
5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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