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Oct4 Antibody#35351

Oct4 Antibody
Oct4 Antibody
是否有货: 有货
产品总价:
产品详情

产品名称Oct4 Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were purified by antigen-affinity chromatography.

应用WB

种属反应性Hu Ms

特异性The antibody detects endogenous levels of total Oct4 protein.

免疫原类型Recombinant Protein

免疫原描述Recombinant fragment corresponding to a region within amino acids 101 and 325 of OCT3/4.

基因/蛋白名称Oct4

别名MGC22487 antibody; OTF-3 antibody; OTF3 antibody; OTF4 antibody; POU5F1 antibody; POU-type homeodomain-containing DNA-binding protein antibody; octamer-binding protein 3 antibody; POU domain transcription factor OCT4 antibody; octamer-binding protein 4 an

数据库入口号Swiss-Prot#:Q01860;
NCBI Gene#:5460

UniprotQ01860

实际分子量39kd

浓度0.48mg/ml

配方Rabbit IgG in 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

保存Store at -20˚C

应用详情

Western blotting: 1:500-1:3000

Sample (20 ug of whole cell lysate)
A: human ESC
10% SDS PAGE
#35351 diluted at 1:500
Sample (30 ug of whole cell lysate)

A: NIH-3T3

10% SDS PAGE

OCT3/4 antibody

#35351 diluted at 1:1000
背景

This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t(6;22)(p21;q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. [provided by RefSeq]

如果您使用该产品35351发表了文章,请通知我们,让我们可以引用您的文献。

et al,Exosomal TRIM3 is a novel marker and therapy target for gastric cancer.In J Exp Clin Cancer Res.On 2018 Jul 21 by Fu H, Yang H et al..PMID:30031392, , (2018),
PMID: 30031392
et al,Tumorigenic hybrids between mesenchymal stem cells and gastric cancer cells enhanced cancer proliferation, migration and stemness.In BMC Cancer on 2015 Oct 24 by Jianguo Xue , Yuan Zhu et al..PMID: 26498753, , (2015),
PMID: 26498753
et al,Activation of mesenchymal stem cells by macrophages prompts human gastric cancer growth through NF-魏B pathway.In PLoS One on 2014 May 13 by Tingting Yang , Xu Zhang et al..PMID:24824968, , (2014),
PMID: 24824968
et al,H. pylori infection-induced MSC differentiation into CAFs promotes epithelial-mesenchymal transition in gastric epithelial cells.In Int J Mol Med on 2013 Dec by Zhang Q, Wang M,et al..PMID:24145921, , (2013),
PMID: 24145921
5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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