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HMGB1 antibody#38424

HMGB1 antibody
HMGB1 antibody
HMGB1 antibody
HMGB1 antibody
是否有货: 货期一周
产品总价:
产品详情

产品名称HMGB1 antibody

来源种属Rabbit

克隆性Polyclonal

亚型IgG

纯化Affinity purification

应用WB,IHC

种属反应性Human,Mouse,Rat

特异性The antibody detects endogenous level of total HMGB1 protein.

免疫原类型Recombinant Protein

免疫原描述A synthetic peptide of human HMGB1 (NP_002119.1).

基因/蛋白名称HMGB1

别名HMG-1;HMG1;HMG3;SBP-1;HMGB1

数据库入口号Uniprot:P09429
GeneID:3146

UniprotP09429

Gene ID3146

实际分子量29KDa

浓度1.0mg/ml

配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.

保存Store at -20˚C. Avoid freeze / thaw cycles.

应用详情
WB 1:500 - 1:2000
IHC 1:50 - 1:200
Western blot analysis of extracts of MCF7 cells, using [KO Validated] HMGB1 Rabbit pAb.
Immunohistochemistry of paraffin-embedded rat brain using HMGB1 Antibody.
Immunohistochemistry of paraffin-embedded human breast cancer using HMGB1 Antibody.
Immunohistochemistry of paraffin-embedded mouse heart using HMGB1 Antibody.
背景
This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein.

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et al,Oleandrin, a cardiac glycoside, induces immunogenic cell death via the PERK/elF2伪/ATF4/CHOP pathway in breast cancer. In Cell Death Dis on 2021 Mar 24 by Xiaoxi Li, Jian Zheng, et al..PMID:33762577, , (2021),
PMID: 33762577
5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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