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位置: 首页 > 抗体 > FZD6 Antibody

FZD6 Antibody#37296

FZD6 Antibody
FZD6 Antibody
是否有货: 有货
产品总价:
产品详情

产品名称FZD6 Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antigen affinity purification.

应用IHC

种属反应性Hu

特异性The antibody detects endogenous levels of total FZD6 protein.

免疫原类型Peptide

免疫原描述Synthetic peptide corresponding to a region derived from internal residues of human frizzled family receptor 6

基因/蛋白名称FZD6

别名FZ6; FZ-6; HFZ6; NDNC10

数据库入口号Swiss-Prot#: O60353
NCBI Gene ID: 8323
Gene Accssion: NP_001158087

UniprotO60353

浓度2.3mg/ml

配方Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.

保存Store at -20˚C

应用详情
Immunohistochemistry: 1:100-1:300
Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using #37296 at dilution 1/60.
Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue using #37296 at dilution 1/60.
背景
This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants, some of which do not encode a protein with a predicted signal peptide.

如果您使用该产品37296发表了文章,请通知我们,让我们可以引用您的文献。

et al,Integrated analysis of novel macrophage related signature in anaplastic thyroid cancer. In Endocrine on 2022 Dec by Yi Luo, Yi-Chen Yang, et al..PMID:36070052, , (2022),
PMID: 36070052
5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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