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IL17A antibody#38147

IL17A antibody
IL17A antibody
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产品总价:
产品详情

产品名称IL17A antibody

来源种属Rabbit

克隆性Polyclonal

亚型IgG

纯化Affinity purification

应用WB,IF,IHC

种属反应性Human,Mouse,Rat

特异性The antibody detects endogenous level of total IL17A protein.

免疫原类型Recombinant Protein

免疫原描述Recombinant fusion protein of human IL17A (NP_002181.1).

基因/蛋白名称IL17A

别名IL17A;CTLA-8;CTLA8;IL-17;IL-17A;IL17

数据库入口号Uniprot:Q16552
GeneID:3605

UniprotQ16552

Gene ID3605

实际分子量17kDa

浓度1.0mg/ml

配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.

保存Store at -20˚C. Avoid freeze / thaw cycles.

应用详情

WB 1:500 - 1:2000
IF 1:50 - 1:200

Western blot analysis of extracts of THP-1 cells, using IL17A antibody.
Immunofluorescence analysis of L929 cells using IL17A Rabbit pAb.
背景

The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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