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位置: 首页 > 磷酸化抗体 > Tau(Phospho-Ser673) Antibody

Tau(Phospho-Ser673) Antibody#11101

Tau(Phospho-Ser673) Antibody
Tau(Phospho-Ser673) Antibody
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产品总价:
产品详情

产品名称Tau(Phospho-Ser673) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

应用WB,IHC,IF,ELISA

种属反应性Hu Ms Rt

特异性Phospho-Tau (S673) Polyclonal Antibody detects endogenous levels of Tau protein only when phosphorylated at S673.

免疫原类型Peptide-KLH

免疫原描述The antiserum was produced against synthesized peptide derived from human Tau around the phosphorylation site of Ser673.

基因/蛋白名称Tau

修饰Phospho

别名MAPT; MTAPT; MTBT1; Neurofibrillary tangle protein; PHF-tau

数据库入口号Swiss-Prot: P10636
NCBI Protein: NP_001116538.1

UniprotP10636

计算分子量50-85kD

浓度1.0mg/ml

配方Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

保存Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

应用详情

WB 1:500 - 1:2000.
IHC 1:100 - 1:300.
ELISA: 1:40000..
IF 1:50-200

Western Blot analysis of NIH-3T3 cells using Phospho-Tau (S673) Antibody diluted at 1:500
Immunohistochemistry analysis of paraffin-embedded human brain, using Tau (Phospho-Ser673) Antibody. The picture on the right is blocked with the phospho peptide.
背景

This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008],

如果您使用该产品11101发表了文章,请通知我们,让我们可以引用您的文献。

et al,Trillium tschonoskii maxim extract attenuates abnormal Tau phosphorylation.Neural Regen Res.In Neural Regen Res.On 2018 May by Luo HB, Shang N. et al..PMID: 29863023, , (2018),
PMID: 29863023
5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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