产品详情
产品名称DDX21 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification
应用IHC
种属反应性Hu
特异性The antibody detects endogenous levels of total DDX21 protein.
免疫原类型protein
免疫原描述Fusion protein of human DDX21
基因/蛋白名称DDX21
别名GUA; GURDB; RH-II/GU; RH-II/GuA
数据库入口号Swiss-Prot#:Q9NR30
NCBI Gene ID:9188
Gene Accssion:BC008071
浓度0.9mg/ml
配方Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
保存Store at -20C
应用详情
Immunofluorescence:1: 20-100
背景
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an antigen recognized by autoimmune antibodies from a patient with watermelon stomach disease. This protein unwinds double-stranded RNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription.?