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JPT1 Antibody#47344

JPT1 Antibody
JPT1 Antibody
是否有货: Yes
产品总价:
产品详情

产品名称JPT1 Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antigen affinity purification

应用IHC

种属反应性Hu, Ms, Rt

特异性The antibody detects endogenous levels of total JPT1 protein.

免疫原类型Peptide

免疫原描述Fusion protein of human JPT1

基因/蛋白名称JPT1

别名HN1; ARM2; HN1A

数据库入口号Swiss-Prot#:Q9UK76
NCBI Gene ID:51155
Gene Accssion:BC001420

浓度0.7

配方Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

保存Store at -20˚C

应用详情

IHC dilution:1: 30-150

The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 47344(JPT1 Antibody) at dilution 1/35.(Original magnification: 200)
The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using 47344(JPT1 Antibody) at dilution 1/35.(Original magnification: 200)
背景

Modulates negatively AKT-mediated GSK3B signaling (PubMed:21323578, PubMed:22155408). Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions (PubMed:25169422). Plays a role in the regulation of cell cycle and cell adhesion (PubMed:25169422, PubMed:25450365). Has an inhibitory role on AR-signaling pathway through the induction of receptor proteosomal degradation (PubMed:22155408).

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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