产品详情
产品名称WSCD2 Antibody
来源种属Mouse
克隆性Monoclonal
克隆性9-F3
纯化ProA affinity purified
应用WB, ICC, IHC
种属反应性Hu
免疫原描述Recombinant protein
别名4933413A10Rik antibody
C530024P05Rik antibody
Gm450 antibody
WSC domain containing 2 antibody
WSC domain containing protein 2 antibody
WSC domain-containing protein 2 antibody
WSCD 2 antibody
WSCD2 antibody
WSCD2_HUMAN antibody
数据库入口号Swiss-Prot#:Q2TBF2
计算分子量70 kDa
配方1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.
保存Store at -20˚C
应用详情
WB: 1:500-1:2,000
IHC: 1:100-1:500
ICC: 1:50-1:200
Western blot analysis of WSCD2 on WSCD2 recombinant protein lysate using anti-WSCD2 antibody at 1/2000 dilution.
Western blot analysis of WSCD2 on human stomach tissue lysate using anti-WSCD2 antibody at 1/1000 dilution.
Immunohistochemical analysis of paraffin-embedded human thyroid tissue using anti-WSCD2 antibody. Counter stained with
Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-WSCD2 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human uterus tissue using anti-WSCD2 antibody. Counter stained with hematoxylin.
ICC staining WSCD2 in SH-SY5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
背景
WSC domain-containing protein 2 (WSCD2) is a 565 amino acid, single-pass membrane protein that contains two WSC domains. The WSC domain is named after the yeast WSC1-WSC4 (cell wall integrity and stress response components 1-4) proteins, which each contain a WSC domain, and is a putative carbohydrate binding domain that spans about 90 amino acids. Containing eight conserved cysteine residues, which are predicted to form disulfide bridges, WSC domains are often found with other domains, such as LDL-receptor class A, PKD and C-type lectin. Two isoforms of WSCD2 exist as a result of alternative splicing events.
背景文献
1.Tong SM et al. Subcellular localization of five singular WSC domain-containing proteins and their roles in Beauveria bassiana responses to stress cues and metal ions. Environ Microbiol Rep 8(2):295-304 (2016).
2.Gao C et al. A genome-wide linkage and association analysis of imputed insertions and deletions with cardiometabolic phenotypes in Mexican Americans: The Insulin Resistance Atherosclerosis Family Study. Genet Epidemiol 41(4):353-362 (2017).
Yes
