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Na+/K+ ATPase Antibody#48318

Na+/K+ ATPase Antibody
是否有货: Yes
产品总价:
产品详情

产品名称Na+/K+ ATPase Antibody

来源种属Mouse

克隆性1G1

纯化ProA affinity purified

应用WB, IP, IF, IHC(P)

种属反应性Hu, Ms, Rt

免疫原描述Amino acids 551-850 of Na+/K+-ATPase α1 of human origin.

别名ATPase Na+/K+ transporting alpha antibody
adenosinetriphosphatase antibody
AT1A1_HUMAN antibody
ATP1A1 antibody
ATP1A4 antibody
ATP1AL2 antibody
ATP1B antibody
ATP1B1 antibody
ATPase Na+/K+ transporting alpha 1 polypeptide antibody
ATPase Na+/K+ transporting alpha 4 polypeptide antibody
ATPase Na+/K+ transporting beta 1 polypeptide antibody
ATPase, Na+/K+ transporting, alpha polypeptide-like 2 antibody
ATPase, Na+/K+ transporting, beta 1 polypeptide antibody
Beta 1-subunit of Na(+),K(+)-ATPase antibody
Na(+)/K(+) ATPase alpha-1 subunit antibody
Na(+)/K(+) ATPase alpha-4 subunit antibody
Na+, K+ ATPase alpha subunit antibody
Na+/K+ ATPase 1 antibody
Na+/K+ ATPase 4 antibody
Na+/K+ ATPase, alpha-D polypeptide antibody
Na, K-ATPase beta-1 polypeptide antibody
Na, K-ATPase, alpha-A catalytic polypeptide antibody
Na,K-ATPase catalytic subunit alpha-A protein antibody
Na,K-ATPase subunit alpha-C antibody
polypeptide-like 2 antibody
Sodium pump 1 antibody
sodium pump 4 antibody
Sodium pump subunit alpha-1 antibody
sodium pump subunit alpha-4 antibody
sodium pump subunit beta-1 antibody
sodium-potassium ATPase catalytic subunit alpha-1 antibody
sodium-potassium ATPase catalytic subunit alpha-4 antibody
sodium-potassium ATPase subunit beta 1 (non-catalytic) antibody
sodium-potassium ATPase, alpha 4 polypeptide antibody
sodium-potassium-ATPase, alpha 1 polypeptide antibody
Sodium/potassium transporting ATPase alpha 1 chain antibody
Sodium/potassium transporting ATPase subunit beta 1 antibody
sodium/potassium-dependent ATPase beta-1 subunit antibody
sodium/potassium-transporting ATPase alpha-4 chain antibody
sodium/potassium-transporting ATPase beta-1 chain antibody
Sodium/potassium-transporting ATPase subunit alpha-1 antibody
sodium/potassium-transporting ATPase subunit alpha-4 antibody

数据库入口号Swiss-Prot#:P05023

计算分子量100-143kDa

配方1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

保存Store at 4˚C

应用详情

WB: 1:2,000-1:1,0000
IHC: 1:50-1:500

IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate)

Western blot analysis of Na+/K+-ATPase α expression in human kidney (A) and human brain (B) tissue extracts.
背景

The ubiquitously expressed sodium/potassium-ATPase (Na+/K+-ATPase) exists as an oligomeric plasma membrane complex that couples the hydrolysis of one molecule of ATP to the importation of three Na+ ions and two K+ ions against their respective electrochemical gradients. As a member of the P-type family of ion motives, Na+/K+-ATPase plays a critical role in maintaining cellular volume, resting membrane potential and Na+-coupled solute transport. Multiple isoforms of three subunits, α, β and γ, comprise the Na+/K+-ATPase oligomer. The α subunit contains the binding sites for ATP and the cations; the glycosylated β subunit ensures correct folding and membrane insertion of the α subunits. The small γ subunit co-localizes with the α subunit in nephron segments, where it increases the affinity of Na+/K+-ATPase for ATP. The β subunit, but not the γ subunit, is essential for normal activity of Na+/K+-ATPase.

背景文献

1. Z?gel, P., et al. 2013. The dimerization domain in outer segment guanylate cyclase is a Ca2+-sensitive control switch module. Biochemistry 52: 5065-5074.
2. Chen, F., et al. 2013. Phospholipase D2 mediates signaling by ATPase class I type 8B membrane 1. J. Lipid Res. 54: 379-385.
3. Bellocci, M., et al. 2010. Azaspiracid-1 inhibits endocytosis of plasma membrane proteins in epithelial cells. Toxicol. Sci. 117: 109-121.

如果您使用该产品48318发表了文章,请通知我们,让我们可以引用您的文献。

et al,The relationship between myodural bridge, atrophy and hyperplasia of the suboccipital musculature, and cerebrospinal fluid dynamicsInSci RepOn2023 Nov 2byHeng Yang # 1, Xiao-Song Wei et al..PMID: 37919345, , (2023),
PMID: 37919345
5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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