产品详情
产品名称FGF2 Rabbit mAb
来源种属Recombinant Rabbit
克隆性 Monoclonal antibody
克隆性JM28-10
纯化ProA affinity purified
应用WB, IP, FC
种属反应性Hu
免疫原描述recombinant protein
别名Basic fibroblast growth factor antibody Basic fibroblast growth factor bFGF antibody BFGF antibody FGF 2 antibody FGF B antibody FGF-2 antibody Fgf2 antibody FGF2 basic antibody FGF2_HUMAN antibody FGFB antibody Fibroblast growth factor 2 (basic) antibody Fibroblast growth factor 2 antibody Fibroblast growth factor, basic antibody HBGF 2 antibody HBGF-2 antibody HBGF2 antibody HBGH 2 antibody HBGH2 antibody Heparin binding growth factor 2 precursor antibody Heparin-binding growth factor 2 antibody Prostatropin antibody
数据库入口号Swiss-Prot#:P09038
计算分子量31 kDa
配方1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
保存Store at -20˚C
应用详情
WB: 1:500-1:1000
IP: 1:50
FC: 1:50-1:100
背景
Fibroblast growth factor-1 (FGF-1), also designated acidic FGF, and fibroblast growth factor-2 (FGF-2), also designated basic FGF, are members of a family of growth factors that stimulate proliferation of cells of mesenchymal, epithe-lial and neuroectodermal origin. Additional members of the FGF family include the oncogenes FGF-3 (Int2) and FGF-4 (hst/Kaposi), FGF-5, FGF-6, FGF-7 (KGF), FGF-8 (AIGF), FGF-9 (GAF) and FGF-10-FGF-23. Members of the FGF family share 30-55% amino acid sequence identity and similar gene structure, and are capable of transforming cultured cells when overexpressed in transfected cells. Cellular receptors for FGFs are members of a second multigene family including four tyrosine kinases, designated Flg (FGFR-1), Bek (FGFR-L), TKF and FGFR-3.
背景文献
1. Park IS et al. Enhancement of Ischemic Wound Healing by Spheroid Grafting of Human Adipose-Derived Stem Cells Treated with Low-Level Light Irradiation. PLoS One 10:e0122776 (2015). 2. Rotschafer JH et al. Modulation of neural stem/progenitor cell proliferation during experimental Herpes Simplex encephalitis is mediated by differential FGF-2 expression in the adult brain. Neurobiol Dis 58:144-55 (2013).
Yes
