免费电话:400-9961-933
邮箱:techcn@signalwayantibody.com
欢迎光临本站
登录 注册 English
位置： 首页 > 重组兔单抗 > GPX4 Rabbit mAb

GPX4 Rabbit mAb#49731

评价
Recombinant
查看说明书
GPX4 Rabbit mAb
GPX4 Rabbit mAb
GPX4 Rabbit mAb
GPX4 Rabbit mAb
GPX4 Rabbit mAb
是否有货： Yes
产品总价:
加入收藏
产品详情 图片 产品描述 发表文献(1) 其它
产品详情

产品名称GPX4 Rabbit mAb

来源种属Recombinant Rabbit

克隆性 Monoclonal antibody

克隆性JU11-31

纯化ProA affinity purified

应用WB,IHC

种属反应性Hu, Ms, Rt, Zebrafish

免疫原描述Recombinant protein

别名Glutathione peroxidase 4 antibody
GPX 4 antibody
GPX-4 antibody
GPX4 antibody
GPX4_HUMAN antibody
GSHPx-4 antibody
MCSP antibody
mitochondrial antibody
PHGPx antibody
Phospholipid hydroperoxidase antibody
Phospholipid hydroperoxide glutathione peroxidase antibody
Phospholipid hydroperoxide glutathione peroxidase mitochondrial antibody
snGPx antibody
snPHGPx antibody
Sperm nucleus glutathione peroxidase antibody

数据库入口号Swiss-Prot#:P36969

计算分子量22 kDa Clone number: JU11-31

配方1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

保存Store at -20˚C

应用详情
WB: 1:500-1:2,000
IHC: 1:50-1:200


Western blot analysis of GPX4 on different lysates using anti-GPX4 antibody at 1/500 dilution.
Positive control:
Lane 1: Rat liver
Lane 2: Mouse kidney
Lane 3: Human liver
Lane 4: Jurkat
Western blot analysis of GPX4 on Zebrafish tissue lysates using anti-GPX4 antibody at 1/500 dilution.
Immunohistochemical analysis of paraffin-embedded rat epididymis tissue using anti-GPX4 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-GPX4 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-GPX4 antibody. Counter stained with hematoxylin.
背景
Glutathione peroxidase (GPx) enzymes are generally selenium-containing tetrameric glycoproteins that help prevent lipid peroxidation of cell membranes. GPx enzymes reduce lipid hydroperoxides to alcohols, and reduce free hydrogen peroxide to water. GPx members are among the few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by the nonsense (stop) codon TGA. There are eight GPx homologs (GPx-1-8). GPx-1, Gpx-2 and Gpx-3 exist as homotetramers. Gpx-4 has a high tendancy to form high molecular weight oligomers.
背景文献
1. Luna-S��nchez M et al. CoQ deficiency causes disruption of mitochondrial sulfide oxidation, a new pathomechanism associated with this syndrome. EMBO Mol Med 9:78-95 (2017).
2. Kagan VE et al. Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis. Nat Chem Biol 13:81-90 (2017).

如果您使用该产品49731发表了文章，请通知我们，让我们可以引用您的文献。

et al,Linoleic Acid–Glucosamine Hybrid for Endogenous Iron-Activated Ferroptosis Therapy in High-Grade Serous Ovarian Cancer. In Mol Pharm on 2022 Sep 5 by Ying Chen, Xiaoming Liao, et al..PMID:35939328, , (2022),
PMID: 35939328
5

操作手册

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu人
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk猴
  • Rb兔
  • B牛
  • D狗
  • P猪
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk鸡

联系我们

Location :

南京市高新开发区星火路10号人才大厦C座

Phone :

400-9961-933
025-58868422

Email Address

techcn@signalwayantibody.com

帮助与技术支持

联系我们

订购帮助

条款

政策

技术支持

新闻动态

快速导航

公司介绍

品牌历史

细胞信号转导

癌症研究

干细胞研究

神经科学

代理商