产品详情
产品名称BOC Polyclonal Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen Affinity Purified
应用IHC
种属反应性Hu
特异性The antibody detects endogenous level of total BOC polyclonal antibody.
免疫原类型protein
免疫原描述Recombinant human Brother of CDO protein (1-125aa)
基因/蛋白名称BOC
别名Protein BOC, BOC, UNQ604/PRO1190
数据库入口号Swiss-Prot#: Q9BWV1
UniprotQ9BWV1
浓度1.0mg/mL
配方PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
保存Store at -20˚C
应用详情
Immunohistochemistry: 1:20 - 1:200
背景
Component of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells. Promotes differentiation of myogenic cells.
背景文献
[1]"The consensus coding sequences of human breast and colorectal cancers."Sjoeblom T., Jones S., Wood L.D., Parsons D.W., Lin J., Barber T.D., Mandelker D., Leary R.J., Ptak J., Silliman N., Szabo S., Buckhaults P., Farrell C., Meeh P., Markowitz S.D., Willis J., Dawson D., Willson J.K.V. Velculescu V.E.Science 314:268-274(2006). [2]"All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner."Kavran J.M., Ward M.D., Oladosu O.O., Mulepati S., Leahy D.J.J. Biol. Chem. 285:24584-24590(2010). [3]"Promyogenic members of the Ig and cadherin families associate to positively regulate differentiation."Kang J.-S., Feinleib J.L., Knox S., Ketteringham M.A., Krauss R.S.Proc. Natl. Acad. Sci. U.S.A. 100:3989-3994(2003).