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CDK14 Antibody#43794

CDK14 Antibody
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产品总价:
产品详情

产品名称CDK14 Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antigen affinity purification

应用WB

种属反应性Hu Ms

特异性The antibody detects endogenous levels of total CDK14 protein.

免疫原类型peptide

免疫原描述Synthetic peptide of human CDK14

基因/蛋白名称CDK14

别名PFTK1; PFTAIRE1

数据库入口号Swiss-Prot#: O94921
NCBI Gene ID: 5218

UniprotO94921

计算分子量53kd

浓度0.2mg/ml

配方Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

保存Store at -20˚C

应用详情
Western blotting: 1:200-1000
Gel: 8%SDS-PAGE
Lysate: 40 μg, Lane: Mouse Pancreas tissue lysate,
Primary antibody:CDK14 antibody at dilution 1/200,
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,
Exposure time: 10 seconds
背景
Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', leading to the activation of the Wnt signaling pathway. Acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3. Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo. May also play a role in meiosis, neuron differentiation and may indirectly act as a negative regulator of insulin-responsive glucose transport.

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et al,Upregulated miR-206 Aggravates Deep Vein Thrombosis by Regulating GJA1-Mediated Autophagy of Endothelial Progenitor Cells. In Cardiovasc Ther on 2022 Mar 18 by Yan Li, Jingping Ge, et al..PMID:35360546, , (2022),
PMID: 35360546
5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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025-58868422

Email Address

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