产品详情
产品名称TIM3 Antibody
来源种属Mouse
克隆性Monoclonal
克隆性IHC003
应用IHC
种属反应性Human
配方Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide
保存Store at 2-8C. Do not freeze.
应用详情
Recommended
working dilution range:1:100 - 1:200
产品描述
T-cell Immunoglobulin and Mucin-Domain-Containing Molecule-3 (TIM3) is present on T-helper type 1 lymphocytes and other immune cells including dendritic cells and natural killer cells. TIM3 is overexpressed in CD4+ tumor-infiltrating lymphocytes, including those with non-small cell lung cancer associated with poor prognoses. TIM3 has recently emerged as a potential target for cancer immunotherapy.
背景文献
Monney L, et al. Nature. 2002; 415:536-41.
Snchez-Fueyo A, et al. Nat Immunol. 2003; 4:1093-101.
Anderson AC. Cancer Immun Res. 2014; 2:393C8.
Gao X, et al. PLoS One. 2012; 7:e30676.
in stock (1 week)
