产品详情
产品名称Tau Antibody
来源种属Mouse
克隆性Monoclonal
克隆性IHC696
应用IHC
种属反应性Human
配方Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide
保存Store at 2-8C. Do not freeze.
应用详情
Recommended
working dilution range:1:100 - 1:200
产品描述
Tau proteins are abundant in neurons of the central nervous system, and function in microtubule stability and organization. Defects in Tau functioning and aggregation of these proteins have been clinically linked to a number of neurodegenerative disorders including Alzheimers disease, Parkinsons disease, Picks disease (PiD), progressive supranuclear palsy (PSP), cortical basal degeneration (CBD), and frontotemporal dementia with parkinsonism linked to chromosome 17 (FTDP-17).
背景文献
Nuobo G, et al. Ann Diagn Pathol. 2017; 25:24-9.
Espinoza M, et al. J Alzheimers Dis. 2008; 14:1-16.
Goedert M, et al. Proc Natl Acad Sci U S A. 1988; 85:4051-5.
Shin RW, et al. Lab Invest. 1991; 64:693-702.
in stock (1 week)
