产品详情
产品名称CD138 Antibody
来源种属Mouse
克隆性Monoclonal
克隆性IHC138
应用IHC
种属反应性Human
配方Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide
保存Store at 2-8C. Do not freeze.
应用详情
Recommended
working dilution range:1:100 - 1:200
产品描述
Cluster of differentiation 138 (CD138), also known as Syndecan-1, is a transmembrane glycoprotein present on the surface of B-cells during late stage differentiation. Anti-CD138 is used to differentiate marginal zone lymphoma from lymphoplasmacytic lymphoma. ALK+ Large B-Cell Lymphoma (LBCL) commonly stains positively for CD138, but not for CD20 and CD79a. Anti-CD138 reacts positively with HHV8-associated primary effusion lymphoma that lack B-cell markers. CD138 is also a useful marker for identifying and enumerating benign, reactive, or malignant plasma cells from the bone marrow biopsy samples.
背景文献
Chilosi M, et al. Mod Pathol. 1999; 12:1101-6.
Sebestyn A, et al. Br J Haematol. 1999; 104:412-9.
Bayer-Garner IB, et al. Mod Pathol. 2001; 14:1052-8.
Said J, et al. WHO Press, Geneva, Switzerland. 261.
OConnell FP, et al. Am J Clin Pathol. 2004; 121:254-63.
Colomo L, et al. Am J Surg Pathol. 2004; 28:736-47.
Carbone A, et al. Blood. 1998; 91:747-55.
2-3 weeks
