产品详情
产品名称DOG1 Antibody
来源种属Mouse
克隆性Monoclonal
克隆性IHC562
应用IHC
种属反应性Human
配方Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide
保存Store at 2-8C. Do not freeze.
应用详情
Recommended
working dilution range:1:100 - 1:200
产品描述
DOG1, also known as Discovered on GIST-1, is a marker that highly specific for gastrointestinal stromal tumor (GIST). Anti-DOG1 is extremely sensitive for the detection of GIST and its diagnosis. Although some GIST stain weakly for c-kit, DOG1 is expressed in the vast majority of GIST cases. Reports have also indicated DOG1 as a marker for salivary acinar and intercalated duct differentiation.
背景文献
Espinosa I, et al. Am J Surg Pathol. 2008; 32:210-8.
Miwa S, et al. J Gastroenterol. 2008; 43:531-7.
Parfitt JR, et al. Histopathology. 2008; 52:816-23.
West RB, et al. Am J Pathol. 2004; 165:107-13.
Lopes LF, et al. Appl Immunohistochem Mol Morphol. 2010; 18:333-7.
Chnevert J, et al. Mod Pathol. 2012; 25:919-29.
3-4 weeks
