产品详情
产品名称Nanog Antibody
来源种属Mouse
克隆性Monoclonal
克隆性IHC634
应用IHC
种属反应性Human
配方Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide
保存Store at 2-8C. Do not freeze.
应用详情
Recommended
working dilution range:1:100 - 1:200
产品描述
Nanog is a homeoprotein that functions with pluripotent factors such as Oct4 and Sox2 to maintain embryonic stem cell pluripotency. Expression of this protein has been noted in seminoma, dysgerminoma, embryonal carcinoma, and other undifferentiated germ cell tumors, while nanog expression is absent in normal adult organ tissues. Anti-Nanog may be useful in distinguishing between undifferentiated germ cell tumors and non-germ cell tumors.
背景文献
Mitsu K, et al. Cell. 2003; 113:631-42.
Chambers I, et al. Cell. 2003; 113:643-55.
Pan G, et al. Cell Res. 2007; 17:42-9.
Hart AH, et al. Cancer. 2005; 104:2092-98.
Chang MC, et al. Int J Gynecol Pathol. 2009; 28:347-55.
in stock (1 week)
