产品详情
产品名称Podoplanin Antibody
来源种属Mouse
克隆性Monoclonal
克隆性IHC650
应用IHC
种属反应性Human
配方Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide
保存Store at 2-8C. Do not freeze.
应用详情
Recommended
working dilution range:1:100 - 1:200
产品描述
Podoplanin is a transmembrane mucoprotein specifically expressed in the endothelium of lymphatic capillaries, while remaining absent from the blood vasculature. The protein is co-localized with VEGFR3/FLT4 in normal skin and kidney. Anti-Podoplanin is useful in the identification of lymphangiomas, Kaposis sarcomas, epithelioid mesotheliomas, hemangioblastomas, seminomas, and some angiosarcomas which likely have lymphatic differentiation.
背景文献
Ordonez NG. Adv Anat Pathol. 2006; 13:83-8.
Ordonez NG. Hum Pathol. 2005; 36:372-80.
Niakosari F, et al. Arch Dermatol. 2005; 141:440-4.
Galambos C, et al. Pediatr Dev Pathol. 2005; 8:191-9.
Fukunaga M. Histopathology. 2005; 46:396-402.
Fogt F, et al. Oncol Rep. 2004; 11:47-50.
Kahn HJ, et al. Mod Pathol. 2002; 15:434-40.
Franke FE, et al. J Cutan Pathol. 2004; 31:362-7.
Kalof AN,et al. Adv Anat Pathol. 2009; 16:62-4.
Chu AY, et al. Mod Pathol. 2005; 18:105-10.
Iczkowski KA, et al. Hum Pathol. 2008; 39:275C81.