产品详情
产品名称Thyroglobulin Antibody
来源种属Mouse
克隆性Monoclonal
克隆性IHC674
应用IHC
种属反应性Human
配方Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide
保存Store at 2-8C. Do not freeze.
应用详情
Recommended
working dilution range:1:100 - 1:200
产品描述
Thyroglobulin is a precursor to the thyroid hormones T4 and T3 and is present in the thyroid follicular cells. Nearly all thyroid follicular carcinomas stain for thyroglobulin and sometimes produce a focal staining pattern. Conversely, poorly differentiated carcinomas and non-thyroid adenocarcinomas do not stain for thyroglobulin, therefore this Thyroglobulin IVD antibody is a useful diagnostic tool for recognizing papillary and follicular thyroid carcinomas. A panel of Anti-Thyroglobulin and Anti-Calcitonin is useful for identifying medullary thyroid carcinomas, whereas a panel of Anti-Thyroglobulin and Anti-TTF1 is useful for distinguishing between primary thyroid and lung neoplasms.
背景文献
Bellet D, et al. J Clin Endocrin Metab. 1983; 56:530-3.
Heffess CS, et al. Cancer. 2002; 95:1869-78.
Bejarano PA, et al. Appl Immunohistochem Mol Morphol. 2000; 8:189-94.
Judkins AR, et al. Hum Pathol. 1999; 30:1373-6.
Hammer SP. Hum Pathol. 1998; 29:1393-402.
in stock (1 week)
