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位置: 首页 > 标记抗体 > Tau (Phospho-Ser356) Conjugated Antibody

Tau (Phospho-Ser356) Conjugated Antibody#C11101

是否有货: 1-2 weeks
产品总价:
产品详情

产品名称Tau (Phospho-Ser356) Conjugated Antibody

来源种属Rabbit

克隆性Polyclonal

应用WB,IHC,IF,ELISA

种属反应性Hu Ms Rt

特异性The antibody detects endogenous level of Tau only when phosphorylated at serine356.

免疫原描述Peptide sequence around phosphorylation site of serine 356 (I-G-S(p)-L-D) derived from Human Tau.

标记Biotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750

激发/发射波长AF350: 346nm/442nm
AF405: 401nm/421nm
AF488: 493nm/519nm
AF555: 555nm/565nm
AF594: 591nm/614nm
AF647: 651nm/667nm
AF680: 679nm/702nm
AF750: 749nm/775nm

别名MAPT;MTAPT;MTBT1;Neurofibrillary tangle protein;PHF-tau

数据库入口号Swiss-Prot#:P10636
NCBI Gene ID:4137
NCBI mRNA#:NM_001123066.2
NCBI Protein#: NP_001116538.1

计算分子量48 62 78

配方0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide

保存Store at 4˚C in dark for 6 months

应用详情

WB: 1:50-1:200
IF:1:50-1:200

产品描述

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

背景

Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

联系我们

Location :

南京市高新开发区星火路10号人才大厦C座

Phone :

400-9961-933
025-58868422

Email Address

techcn@signalwayantibody.com