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位置: 首页 > 标记抗体 > YAP65 Conjugated Antibody

YAP65 Conjugated Antibody#C48351

是否有货: 1-2 weeks
产品总价:
产品详情

产品名称YAP65 Conjugated Antibody

来源种属Rabbit

克隆性Polyclonal

应用WB, IF

种属反应性Hu, Ms, Rt

免疫原描述Amino acids 206-330 mapping near the C-terminus of YAP of human origin.

标记Biotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750

激发/发射波长AF350: 346nm/442nm
AF405: 401nm/421nm
AF488: 493nm/519nm
AF555: 555nm/565nm
AF594: 591nm/614nm
AF647: 651nm/667nm
AF680: 679nm/702nm
AF750: 749nm/775nm

别名65 kDa Yes associated protein antibody
65 kDa Yes-associated protein antibody
COB1 antibody
YAp 1 antibody
YAP 65 antibody
YAP antibody
YAP1 antibody
YAP1_HUMAN antibody
YAP2 antibody
YAP65 antibody
yes -associated protein delta antibody
Yes associated protein 1 65kDa antibody
Yes associated protein 1 antibody
Yes associated protein 2 antibody
yes associated protein beta antibody
YKI antibody
Yorkie homolog antibody

数据库入口号Swiss-Prot#:P46937

计算分子量65kDa

配方0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide

保存Store at 4˚C in dark for 6 months

应用详情
WB: 1:50-1:200
IF:1:50-1:200
背景
The Yes-associated protein, otherwise known as YAP, is a 14-3-3-binding molecule that was originally recognized by virtue of its ability to bind to the SH3 domain of Yes. The binding of YAP to 14-3-3 requires the phosphorylation of a homologous serine residue (Ser 112) in the YAP 14-3-3-binding motif. The highly conserved and ubiquitously expressed 14-3-3 proteins regulate differentiation, cell cycle progression and apoptosis by binding intracellular phosphoproteins involved in signal transduction. YAP may link events at the plasma membrane and cytoskeleton to inhibition of transcription in the nucleus in a manner regulated by 14-3-3 proteins. YAP shares homology with the WW domain of TAZ, transcriptional co-activator with PDZ-binding motif, which functions as a transcriptional co-activator by binding to the PPXY motif present in transcription factors. YAP is expressed at high levels in the lung, placenta, prostate, ovary and testis.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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400-9961-933
025-58868422

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