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位置: 首页 > 标记抗体 > VPS35 Conjugated Antibody

VPS35 Conjugated Antibody#C49784

是否有货: 1-2 weeks
产品总价:
产品详情

产品名称VPS35 Conjugated Antibody

来源种属Rabbit

克隆性Monoclonal

应用WB, IF, FC

种属反应性Hu, Ms

免疫原描述Recombinant protein

标记Biotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750

激发/发射波长AF350: 346nm/442nm
AF405: 401nm/421nm
AF488: 493nm/519nm
AF555: 555nm/565nm
AF594: 591nm/614nm
AF647: 651nm/667nm
AF680: 679nm/702nm
AF750: 749nm/775nm

别名DKFZp434E1211 antibody
DKFZp434P1672 antibody
FLJ10752 antibody
FLJ13588 antibody
FLJ20388 antibody
hVPS35 antibody
Maternal embryonic 3 antibody
Maternal-embryonic 3 antibody
MEM 3 antibody
MEM3 antibody
PARK17 antibody
TCCCTA00141 antibody
Vacuolar protein sorting 35 (yeast) antibody
Vacuolar protein sorting 35 antibody
Vacuolar protein sorting 35 homolog antibody
Vacuolar protein sorting associated protein 35 antibody
Vacuolar protein sorting-associated protein 35 antibody
Vesicle protein sorting 35 antibody
VPS 35 antibody
VPS35 antibody
VPS35_HUMAN antibody

数据库入口号Swiss-Prot#:Q96QK1

计算分子量91 kDa

配方0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide

保存Store at 4˚C in dark for 6 months

应用详情
WB: 1:50-1:200
IF:1:50-1:200
FC: 1:50-1:200
背景
Vacuolar sorting proteins (VPSs) are required for proper trafficking of endocytic and biosynthetic proteins to the vacuole and play an important role in the budding process of cells. VPS35 (vacuolar protein sorting 35), also known as MEM3, is the 796 amino acid human homolog of the S. cerevisiae Vps35 protein. Localized to the cytoplasm and to the peripheral membrane, VPS35 is an essential component of the retromer complex which is involved in retrieval of lysosomal enzyme receptors from endosomes to the trans-Golgi network. VPS35 is expressed ubiquitously with highest expression in heart, placenta, brain, testis, kidney, colon, ovary and spleen. In addition to its crucial role in the retromer complex, VPS35 is part of a subcomplex that is required to regulate transcytosis of the polymeric immunoglobulin receptor from the basolateral to the apical surface of epithelial cells and hepatocytes.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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