HMGCS2 Polyclonal Antibody - SAB

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HMGCS2 Polyclonal Antibody#29188

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产品详情

产品名称HMGCS2 Polyclonal Antibody

来源种属Rabbit

克隆性Polyclonal

亚型IgG

纯化Affinity purification

应用WB,IHC,IF

种属反应性Human,Mouse,Rat

免疫原描述Recombinant fusion protein of human HMGCS2 (NP_005509.1).

别名HMGCS2

数据库入口号GeneID:3158
Swiss Prot:P54868

计算分子量50kDa/52kDa/56kDa

实际分子量50kDa

浓度1.0mg/ml

配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 81% glycerol.

保存Store at -20˚C. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.34.

应用详情

WB 1:500 - 1:2000
IHC 1:50 - 1:100
IF 1:50 - 1:100

Western blot analysis of extracts of various cell lines, using HMGCS2 antibody at 1:1000 dilution.

Immunohistochemistry of paraffin-embedded human thyroid cancer using HMGCS2 antibody at dilution of 1:100 .

Immunohistochemistry of paraffin-embedded human colon carcinoma using HMGCS2 antibody at dilution of 1:100 .

Immunofluorescence analysis of rat liver using HMGCS2 Polyclonal Antibody at dilution of 1:100 . Blue: DAPI for nuclear staining.

Immunofluorescence analysis of human liver using HMGCS2 Polyclonal Antibody at dilution of 1:100 . Blue: DAPI for nuclear staining.

Immunofluorescence analysis of mouse liver using HMGCS2 Polyclonal Antibody at dilution of 1:100 . Blue: DAPI for nuclear staining.

背景

The protein encoded by this gene belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting. Mutations in this gene are associated with HMG-CoA synthase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

如果您使用该产品29188发表了文章，请通知我们，让我们可以引用您的文献。

et al,Quantitative proteomics analysis based on data-independent acquisition reveals the effect of Shenling Baizhu powder (SLP) on protein expression in MAFLD rat liver tissueInClin ProteomicsOn2023 Dec 1bySufei Song?1,?Jixian Zheng?2 et al..PMID:?38036981, , (2023),
PMID: 38036981

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应用

WB免疫印迹
IHC免疫组化
IF免疫荧光
ICC免疫细胞化学
FC流式细胞
IP免疫沉淀
E酶联免疫吸附法
DB免疫斑点法
ChIP染色质免疫沉淀
GICA胶体金免疫层析法
NC阴性对照

种属反应性

Hu人
Ms小鼠
Rt大鼠
Dm果蝇
C线虫
Mk猴
Rb兔
B牛
D狗
P猪
Hm仓鼠
ChHm中国仓鼠
Chk鸡

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HMGCS2 Polyclonal Antibody#29188

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