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位置: 首页 > 抗体 > ZBTB48 Rabbit Polyclonal Antibody

ZBTB48 Rabbit Polyclonal Antibody#55213

ZBTB48 Rabbit Polyclonal Antibody
是否有货: Yes
产品总价:
产品详情

产品名称ZBTB48 Rabbit Polyclonal Antibody

来源种属Rabbit

克隆性Polyclonal

亚型IgG

纯化Affinity purification

应用WB

种属反应性Human,Mouse

免疫原描述Recombinant fusion protein of human ZBTB48 (NP_005332.1).

别名ZBTB48;HKR3;TZAP;ZNF855;pp9964

数据库入口号Uniprot:P10074
GeneID:3104

UniprotP10074

Gene ID3104

计算分子量77kDa

实际分子量77kDa

配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.

保存Store at -20˚C. Avoid freeze / thaw cycles.

应用详情
WB 1:500 - 1:2000
Western blot analysis of extracts of various cell lines, using ZBTB48 antibody.
背景
Telomere-binding protein that acts as a regulator of telomere length. Directly binds the telomeric double-stranded 5'-TTAGGG-3' repeat. Preferentially binds to telomeres that have a low concentration of shelterin complex and acts as a regulator of telomere length by initiating telomere trimming, a process that prevents the accumulation of aberrantly long telomeres. Also acts as a transcription regulator that binds to promoter regions. Regulates expression of a small subset of genes, including MTFP1. Regulates expression the J and/or S elements in MHC II promoter. Acts as a negative regulator of cell proliferation by specifically activating expression of ARF, a tumor suppressor isoform of CDKN2A.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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