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位置: 首页 > 磷酸化抗体 > SQSTM1/p62 (Phospho-Ser) Antibody

SQSTM1/p62 (Phospho-Ser) Antibody#SAB649

是否有货: Yes
产品总价:
产品详情

产品名称SQSTM1/p62 (Phospho-Ser) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化The antibody was purified from rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.

应用WB

种属反应性Human

特异性SQSTM1/p62(Phospho-Ser28) Antibody detects endogenous levels of NFKBIA only when phosphorylated at Ser28.

免疫原描述A synthesized peptide derived from human SQSTM1/p62 around the phosphorylation site of Ser28.

别名SQSTM1,ORCA, OSIL,Sequestosome-1,Ubiquitin-binding protein p62,EBIAP

UniprotQ13501

Gene ID8878

计算分子量47kd

浓度1 mg/ml

配方Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl,0.02% sodium azide and 50% glycerol.

保存Store at --20˚C/1 year

应用详情
Western Blot: 1/500 - 1/2000
背景
Autophagy receptor required for selective macroautophagy (aggrephagy). Functions as a bridge between polyubiquitinated cargo and autophagosomes. Interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family (PubMed:16286508, PubMed:20168092, PubMed:24128730, PubMed:28404643, PubMed:22622177). Along with WDFY3, involved in the formation and autophagic degradation of cytoplasmic ubiquitin-containing inclusions (p62 bodies, ALIS/aggresome-like induced structures). Along with WDFY3, required to recruit ubiquitinated proteins to PML bodies in the nucleus

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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