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位置: 首页 > 磷酸化抗体 > NFKBIA (Phospho-Thr291) Antibody

NFKBIA (Phospho-Thr291) Antibody#SAB667

是否有货: Yes
产品总价:
产品详情

产品名称NFKBIA (Phospho-Thr291) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化The antibody was purified from rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.

应用WB

种属反应性Human

特异性NFKBIA (Phospho-Thr291) Antibody detects endogenous levels of NFKBIA only when phosphorylated at threonine 291.

免疫原描述A synthesized peptide derived from human NFKBIA around the phosphorylation site of T291.

别名NF-kappa-B inhibitor alpha,I-kappa-B-alpha,IkB-alpha, IkappaBalpha

UniprotP25963

Gene ID4792

实际分子量36kSa

浓度1 mg/ml

配方Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl,0.02% sodium azide.

保存Store at --20˚C/1 year

应用详情
Western Blot: 1/500 - 1/2000
背景
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

联系我们

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Email Address

techcn@signalwayantibody.com