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位置: 首页 > 抑制剂 > Paliperidone

Paliperidone#S0076

是否有货: The lead time is currently 7-30 days.
产品总价:询价
产品详情

产品名称Paliperidone

简述Inhibitors

纯化99.00%

生物活性Paliperidone(Invega) is an atypical antipsychotic. Chemically, paliperidone is the primary active metabolite of the older atypical antipsychotic risperidone. It is indicated for the acute and maintenance treatment of schizophrenia.

基因/蛋白名称5-HT Receptor antagonist; Adrenergic Receptor antagonist; Dopamine Receptor antagonist; Histamine Receptor antagonist

CAS号144598-75-4

计算分子量426.48

配方C23H27FN4O3

保存3 years -20˚C powder;2 years -80˚C in solvent;

产品描述
Research Area:Nervous system
SMILES:CC1=C(CCN2CCC(CC2)C2=NOC3=C2C=CC(F)=C3)C(=O)N2CCCC(O)C2=N1
Pathways:GPCR/G Protein; Immunology/Inflammation; Neuroscience
Receptor:5-HT; β-adrenergic receptor; Dopamine; H1 receptor
Boling pt:612.3C?
Melting pt:158-160C
Solubility:DMSO: 4mg/ml(9.38 mM);Water: <1mg/ml;Ethanol: <1mg/ml
Appearance:Faint Yellow Powder
Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.
背景文献
1. Richelson E, Souder T. Life Sci. 2000 Nov 24;68(1):29-39.

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5

注释

应用

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  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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