产品名称Eplerenone

简述Inhibitors

纯化98.00%

生物活性Eplerenone, an aldosterone receptor antagonist similar to spironolactone, has been shown to produce sustained increases in plasma renin and serum aldosterone, consistent with inhibition of the negative regulatory feedback of aldosterone on renin secretion. The resulting increased plasma renin activity and aldosterone circulating levels do not overcome the effects of eplerenone. Eplerenone selectively binds to recombinant human mineralocorticoid receptors relative to its binding to recombinant human glucocorticoid, progesterone and androgen receptors.

基因/蛋白名称Glucocorticoid Receptor inhibitor

CAS号107724-20-9

计算分子量414.49

配方C24H30O6

保存3 years -20˚C powder;2 years -80˚C in solvent;