产品详情
产品名称Voriconazole
简述Inhibitors
纯化99.00%
生物活性Voriconazole is an Azole Antifungal. Voriconazole is a new triazole derivative similar to fluconazole and itraconazole that acts by inhibiting fungal cytochrome P-450-dependent, 14-alpha-sterol demethylase-mediated synthesis of ergosterol.
基因/蛋白名称Antifection inhibitor
CAS号137234-62-9
计算分子量349.31
配方C16H14F3N5O
保存3 years -20˚C powder;2 years -80˚C in solvent;
产品描述
Research Area:Immunology
SMILES:C[C@@H](C1=NC=NC=C1F)[C@](CN2C=NC=N2)(C3=C(C=C(C=C3)F)F)O
Pathways:Microbiology&virology
Receptor:14-α Demethylase
Boling pt:508.6C
Melting pt:127-130C
Solubility:Ethanol: 20 mg/mL (57.25 mM); DMSO: 70 mg/mL (200.39 mM)
Appearance:White Powder
Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.
背景文献
1. Espinel-Ingroff A, et al. J Clin Microbiol, 1998, 36(1), 198-202.
The lead time is currently 7-30 days.
