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位置: 首页 > 抑制剂 > Quinidine hydrochloride

Quinidine hydrochloride#S0266

是否有货: The lead time is currently 7-30 days.
产品总价:询价
产品详情

产品名称Quinidine hydrochloride

简述Inhibitors

纯化99.00%

生物活性An optical isomer of quinine, extracted from the bark of the Cinchona tree and similar plant species. This alkaloid dampens the excitability of cardiac and skeletal muscles by blocking sodium and potassium currents across cellular membranes. It prolongs cellular action potential, and decreases automaticity. Quinidine also blocks muscarinic and alpha-adrenergic neurotransmission.

基因/蛋白名称Potassium Channel inhibitor; Sodium Channel inhibitor

CAS号6151-40-2

计算分子量378.89

配方C20H27ClN2O3

保存3 years -20˚C powder;2 years -80˚C in solvent;

产品描述
Research Area:Immunology
SMILES:COC1=CC2=C(C=CN=C2C=C1)[C@@H]([C@H]3C[C@@H]4CCN3C[C@@H]4C=C)O.O.Cl
Pathways:Membrane transporter/Ion channel
Receptor:Potassium Channel; Sodium Channel
Boling pt:495.9C?
Melting pt:258-259C
Solubility:DMSO: 10 mM
Appearance:White Powder
Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.
背景文献
1. Stokoe KS, et al. J Physiol. 2007 Jan 1;578(Pt 1):69-84.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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