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位置: 首页 > 抑制剂 > Quinacrine dihydrochloride

Quinacrine dihydrochloride#S0942

是否有货: The lead time is currently 7-30 days.
产品总价:询价
产品详情

产品名称Quinacrine dihydrochloride

简述Inhibitors

纯化98.00%

生物活性An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2..

基因/蛋白名称DNA Alkylation inhibitor; Histamine Receptor inhibitor; Phospholipase inhibitor

CAS号1969/5/6

计算分子量472.88

配方C23H30CLN3O2HCl

保存3 years -20˚C powder;2 years -80˚C in solvent;

产品描述
Research Area:Immunology
SMILES:[H+].[H+].[Cl-].[Cl-].CCN(CC)CCCC(C)NC1=C2C=C(OC)C=CC2=NC2=C1C=CC(Cl)=C2
Pathways:GPCR/G Protein; DNA Damage/DNA Repair; Metabolism; Immunology/Inflammation; Neuroscience
Receptor:DNA; Histamine N-methyltransferase; PLA2; PLCLP
Boling pt:
Melting pt:249-251C
Solubility:Ethanol: 28 mg/mL (59.21 mM); Water: 53 mg/mL (112.07 mM); DMSO: 14 mg/mL (29.6 mM)
Appearance:Yellow Powder
Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.
背景文献
1. Nuttle LC, et al. Am J Physiol. 1999 Apr;276(4 Pt 2):H1289-94.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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