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位置: 首页 > 抑制剂 > Lenalidomide (CC-5013)

Lenalidomide (CC-5013)#S1642

是否有货: The lead time is currently 7-30 days.
产品总价:询价
产品详情

产品名称Lenalidomide (CC-5013)

简述Inhibitors

纯化98.00%

生物活性Lenalidomide (initially known as CC-5013 and marketed as Revlimid? by Celgene) is a derivative of thalidomide introduced in 2004. It was initially intended as a treatment for multiple myeloma, for which thalidomide is an accepted therapeutic modality, but has also shown efficacy in the hematological disorders known as the myelodysplastic syndromes. FDA approved on December 27, 2005.

基因/蛋白名称TNF inhibitor

CAS号191732-72-6

计算分子量259.26

配方C13H13N3O3

保存3 years -20˚C powder;2 years -80˚C in solvent;

产品描述

Research Area:Cancer
SMILES:NC1=CC=CC2=C1CN(C1CCC(=O)NC1=O)C2=O
Pathways:Apoptosis
Receptor:TNF-α
Boling pt:
Melting pt:269-271C
Solubility:DMSO: 35 mg/mL
Appearance:White Powder
Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

背景文献

1. Muller GW, et al. Bioorg Med Chem Lett, 1999, 9(11), 1625-1630.

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5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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